- Transfusion Technology
Compatible: fully compatible with Fresenius Kabi COM.TEC® and other centrifuge systems 1 In the ESPIRA study, the IgEnio ® adsorber was combined with the Fresenius Kabi COM.TEC ® cell separator to perform a specific type of immunoapheresis (IA) in patients with severe atopic asthma. Fresenius Kabi is a global health care company that specializes in lifesaving medicines and technologies for infusion, transfusion and clinical nutrition. Our products are used to help care for critically and chronically ill patients. Apheresis Collection Systems Fresenius Kabi provides blood centers with a full suite of apheresis technologies that help specialists efficiently collect their community’s most needed components, so patients can receive the blood components they need.
In-line filter system – a blood bag system for leukocyte filtration
- Fresenius Medical Care Fresenius COM.TEC Blood Cell Separator 510(k) Premarket Notification Summary of Safety and Effectiveness Intended Use - Fresenius ASIO04 The Fresenius AS 104 Cell Separator is intended for use in apheresis procedures involving donors and patients. The fields of application are as follows: Platelet collection Plasma exchange.
- Centrifugal Apheresis Systems Intermittent / Discontinuous Flow Haemonetics: PCS-2, MCS+ 8150 and 9000, Cymbal Therakos UVAR-XTS Continuous Flow TerumoBCT: COBE Spectra, Trima, Trima Accel, Spectra Optia Fenwal (Fresenius Kabi): Amicus, Alyx. Fresenius Kabi: AS 104, Com.Tec.
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For blood donation and component processing, Fresenius Kabi offers medical devices. These include cell separators (apheresis systems), autotransfusion devices, blood bag and filter systems as well as related blood processing equipment. Keygen superior drummer 2.0 mac torrent. Component processing consists of the separation and collection of certain blood cells.
Blood Cell Separator
The Fresenius cell separator has three areas of application:
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- Donate blood cells: obtaining cells from the blood of a donor for transfusion, for example for treating coagulation dysfunctions or leukemia patients
- Remove cancer cells: removing diseased cells or blood plasma from the blood of a patient with leukemia or an autoimmune disease, i. e., in patients with disorders where the body produces defense substances against its own cells
- Collect a patient’s cells: collecting cells from a patient's own blood for re-infusion, for example prior to operation.
Donate blood cells
A cell separator is primarily used to collect blood platelets or thrombocytes. While red blood cells mainly transport oxygen and other blood cells ward off pathogens, thrombocytes play an important role in blood clotting. Patients with too few thrombocytes suffer from an inability of the blood to coagulate properly. Injuries can lead to potentially dangerous bleeding. One example of the cause of thrombocyte deficiency is cancer therapy. Doctors infuse patients with healthy donor thrombocytes following treatment.
Thrombocytes are obtained most effectively with a blood cell separator. The machine, which works like a centrifuge, gently separates thrombocytes from the other blood components. Components that are not needed are immediately returned to the donor. Because only the thrombocytes are taken, which regenerate much quicker than red blood cells, a donor may donate much more frequently than in regular whole-blood donations. The cell separator also allows a much larger number of thrombocytes to be collected per donation than in whole blood. All patients who require a large number of thrombocytes can benefit double from the procedure – regular transfusions include thrombocytes from several sources but a blood cell separator can reduce the number of donors needed per transfusion. Xln audio addictive drums crack free. This allows a doctor to select thrombocytes from the most appropriate donors. This is important because the efficacy of the thrombocytes improves when the blood groups of donors and recipients match.Remove cancer cells
A cell separator can separate thrombocytes from other blood cells; it can also support the treatment of leukemia patients by removing diseased cells directly from the blood. Since leukemic cancer cells quickly reproduce, this procedure cannot heal a patient. But it relieves the strain on the kidneys by considerably lowering the number of destroyed cancer cells that must be removed from the blood following treatment.Collect a patient's cells
Although rarely used, another application of the blood cell separator is quickly gaining in importance. Doctors can use the device to remove stem cells from the blood of a cancer patient. Through pre-treatment bone marrow stem cells start to reproduce and partially move into the blood stream. These stem cells can be collected almost like platelets. This way surgery to obtain stem cells directly from bone marrow can be avoided.
The treatment subsequently used to combat cancer cells damage the stem cells from which all other blood cells are made. If the patient receives healthy stem cells after chemotherapy, healthy blood cells can develop quicker, for example the platelets that are important for hemostasis and coagulation.
Fresenius Kabi Apheresis Machine Manual Pdf
Blood bag systems
Blood bag systems are the foundation for worldwide blood supply by 'classical' blood donation. More than 90 percent of all blood donations are processed in these systems that consist of up to six different bags with variable functions.
A combination of bags with venous cannulae and integrated needle protection, pre-donation sampling pouches and different filtration devices form the basis for highly professional whole blood collection systems. They allow producing different blood component preparations according to national and international standards. Blood donation and processing with these systems is supplemented by other devices such as automated scales and blood separators, sterile docking systems and sealers to name a few.
A combination of bags with venous cannulae and integrated needle protection, pre-donation sampling pouches and different filtration devices form the basis for highly professional whole blood collection systems. They allow producing different blood component preparations according to national and international standards. Blood donation and processing with these systems is supplemented by other devices such as automated scales and blood separators, sterile docking systems and sealers to name a few.
- Apheresis
Adsorber production at Fresenius Medical Care in Krems, Austria.
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The principle behind treating blood outside the body can be used for more than just treating chronic kidney failure. This method of treatment can also be used to temporarily support the liver and filter certain pathogens from the blood. Liver support therapy and adsorber therapy are similar to hemodialysis.
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Liver Support Therapy
The liver fulfills vital functions within the body including the production of proteins, the conversion and storage of metabolic products and – together with the kidneys – the detoxification of the blood. Acute or chronic liver failure can be caused by hepatitis, excessive alcohol consumption, poisoning, cancer or other reasons. A liver transplant is the only effective therapy for severe liver failure to date. However, in the past few years, scientists have developed blood-cleaning procedures that allow a patient to survive for at least several days or even weeks to bridge the time until the organ has recovered, or a donor organ has been found.
The Prometheus system – developed by Fresenius scientists in cooperation with the Danube University Krems – is one of the newest liver-support systems on the market. In contrast to dialysis used in kidney failure, liver failure also requires the removal of toxins that are bound to albumin, a transporting protein in the blood. Thus, the Prometheus system combines a typical dialysis procedure with an adsorber treatment. At first, the Prometheus machine pumps the blood through a newly developed filter (AlbuFlow) that retains blood cells and large protein molecules. The blood liquid, or plasma, along with albumin and smaller protein molecules is then fed through two adsorbers that separate toxins from the albumin and bind them. Following adsorption, the blood plasma with the detoxified albumin is joined with the blood cells retained by the AlbuFlow filter. Finally, the blood is dialyzed to remove the remaining water-soluble toxins, and the filtered blood is then reintroduced into the patient.
Adsorber Therapy
Adsorber therapy is a new and innovative therapy concept for selectively removing undesirable and pathogenic substances from blood outside the body without supplying substances. It is generally used for patients with diseases where drug treatment methods have failed or were not enough.
In all adsorber treatments, the blood flows through a tube from a vein in the arm of the patient into the adsorber. The various adsorbers contain different materials which, like a sponge, selectively extract the unwanted and pathogenic substances from the blood. The cleansed blood is then returned to the patient through a vein in the other arm. A special machine pumps the blood through the adsorber and monitors the blood circulation outside the body.